Pharmacokinetic actions mediated through the cytochrome P540 (CYP)System
Addressing Pharmacokinetic actions mediated through the hepatic and gut drug-metabolizing system known as the cytochrome P540 (CYP) enzyme system.
1. Please state what the CYP 2D6 enzyme is, why it is important, and what it does in the body. List common medications, foods, herbs, and/or substances that inhibit and induce this enzyme, and include any major substrates (specifically psychiatric drugs you would encounter) and any important medication restrictions regarding this enzyme. (1 page and 1 reference)
2. Please state what the CYP 3A4 enzyme is, why it is important, and what it does in the body. List common medications, foods, herbs, and/or substances that inhibit and induce this enzyme, and include any major substrates (specifically psychiatric drugs you would encounter) and any important medication restrictions regarding this enzyme. (1 page and 1 reference)
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