How to write a nursing discussion on Rheumatoid Arthritis
Q1. Describe the immunopathogenesis of the joint changes that occur in RA.
Rheumatoid arthritis (RA) is an autoimmune disease that mainly affects joints in the hands, wrists, and knees (Pope, 2020). The pathogenesis of RA is complex because it involves a series of interactions between genetic, environmental, and immunologic factors. It is established that immune cells like anti-citrullinated protein antibodies (ACPAs) and cytokines exist and increase gradually in circulation before RA (Yap et al., 2018). The interaction of these cells in the joints increases vascular permeability in the synovium and activates synovial cells. The result is the activation of small-molecule mediators of inflammation like chemokines and matrix metalloproteinases (MMPs) that initiate arthritis (Yap et al., 2018). The synovial lining is not an effective barrier to preventing disease progression.
Q2. What is the significance of her RF test results?
The rheumatoid factor (RF) test looks for the presence of proteins made by the immune system that may be the source of autoimmune disorders. RF is important to diagnose RA and determine the extent of the disease (Yap et al., 2018). Although not all cases of RA contain RF, individuals with RF-positive results tend to manifest with bone erosion and have a poor prognosis.
Q3. How do her complaints of general fatigue and weight loss related to the RA disease process
Weight loss and fatigue are common symptoms in individuals with RA (Yap et al., 2018). It is established that inflammatory cells like cytokines also impact metabolism and contribute to muscle breakdown. Secondly, RA can decrease appetite leading to insufficient food intake that leads to weight changes. More than three-quarters of patients with RA experience fatigue (Pope, 2020). Fatigue can be a result of pain, sleep disturbance, and depressed mood.
References
Pope J. E. (2020). Management of fatigue in rheumatoid arthritis. RMD Open, 6(1), e001084. https://doi.org/10.1136/rmdopen-2019-001084
Yap, H. Y., Tee, S. Z., Wong, M. M., Chow, S. K., Peh, S. C., & Teow, S. Y. (2018). Pathogenic role of immune cells in rheumatoid arthritis: Implications in clinical treatment and biomarker development. Cells, 7(10), 161.
https://doi.org/10.3390/cells7100161
Related Posts:
- Link the theory you developed in Weeks 2 and 5 with the Metaparadigm of Nursing. Each of the elements of the Metaparadigm should be represented in your theory. Revise your theory if necessary to include each of the components of the Metaparadigm.
- Assignment: Literature Review: The Use Of Clinical Systems To Improve Outcomes And Efficiencies AND Discussion: The Inclusion Of Nurses In The Systems Development Life Cycle
- Discuss the health care support systems available in your community for someone of this culture. If no support systems are available in your community, identify a national resource.
- Application: Systems Theory
- MN502-4: Develop a philosophy that supports advanced nursing practice reflecting the values, beliefs, and cultural competencies relative to nursing practice, science, and theory.
- Nursing Theory (Situation-Specific Theory Evaluation Criteria)
- Nursing Theory Assignment: Discussion: Applying Florence Nightingale’s Theory to Your Life.
- Identify The Professional Code Of Ethics For Your Professional Specialty Or A Specialty That You Are Interested In, Describe The Decision Criteria, And Analyze Each Theory Using Examples And The Ethical Theory Matrix Template.
- PowerPoint On Nursing Theory Peaceful End Of Life Nursing Theory By Cornelia Ruland And Shirley Moore
- This Is A Continuation Of Your Unit 5 Assignment. Drawing Upon The Theory You Chose For Your Presentation (It Was Bureaucratic Management Theory,Allached The Slides) You Are To Compose An APA-Formatted Paper Addressing The Following Questions:
- Research GASB Statement No. 56: how government accounting journal entries might differ from for-profit journal entries
- LABOR UNION ISSUES
- Alternative Geographies:What if the Soviet Union won the Cold war?
- Terrorism and Soviet Union
- In the Persuasive Research Paper, you will simply want to take a position on an issue of your choice, using research to support your position and to try to convince others to adopt your position.
- Through the lens of Nightingale?s theory, discuss hoarding and what positive changes nurses might try to facilitate in this environment Custom Essay
- Your assignment is to write a 2-3 page essay in which you address the scenario below. Suppose that you have a house guest from another country. He is curious about the lifestyles that we tend to lead in the United States. He wants to know why there seems to be such a big problem with nutrition and lack of exercise. Explain to him why nutrition and exercise are important to the health of our society as a whole. Case assignment expectations: Use information from the modular background readings as well as any good quality resource you can find. Please cite all sources and provide a reference list at the end of your paper. LENGTH: 2-3 pages typed and double-spaced. The following items will be assessed in particular: 1. Your ability to explain why lifestyle factors such as nutrition and exercise are important to the health of a society 2. Some in-text references to modular background readings (APA formatting preferred) Be sure that your opinion is justified with evidence from the literature. Try to use several scholarly references for each assignment. All references should be cited properly in the text of the paper as well as at the end. Please limit your response to 3 pages maximum. Assignments are due on the Monday after a module ends.
- What do you think are the possible major tensions that exist when a pharmaceutical firm forms an alliance with a biotechnology firm? • How would you try to address those tensions?
- Write a description of a NURSING group with which you have been or are currently involved. Assess where the group is in terms of the four stages of group formation.
- Identity Formation
